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Patients were recruited between September 1987 and January 2001. Date of analysis was December 31, 2009, with median (midpoint) follow-up of 14.7 years. Inclusion criteria were age 37 to 60 years and a body mass index of at least 34 in men and at least 38 in women. Surgery patients underwent gastric bypass (13.2 percent), banding (18.7 percent), or vertical banded gastroplasty (68.1 percent), and controls received usual care in the Swedish primary health care system. Physical and biochemical examinations and database cross-checks were undertaken at preplanned intervals. The average changes in body weight after 2, 10,15, and 20 years were -23 percent, -17 percent, -16 percent, and -18 percent in the surgery group and 0 percent, 1 percent, -1 percent, and -1 percent in the control group, respectively.
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Taken with previous reports, the results, write the authors, &8220;demonstrate that there are many benefits to bariatric surgery and that some of these benefits are independent of the degree of the surgically induced weight loss.&8221;
In an accompanying editorial, Edward Livingston writes that &8220;because the expected health benefits do not necessarily exceed the risks of weight loss operations, obese patients without other weight-related complications generally should not undergo bariatric surgery.&8221; He suggests that the NIH convene a new expert panel &8220;to rigorously assess the available evidence and provide updated recommendations for bariatric procedures for the treatment of obesity.&8221;
Most epidemiological studies have shown that obesity is associated with increased cardiovascular events and death. Weight loss might protect against cardiovascular events, but solid evidence is lacking, according to background information in the article.
Bariatric surgery was associated with reduced number of tal heart attack deaths (22 in the surgery group vs. 37 in the control group), with analysis indicating that bariatric surgery was related both to reduced tal heart attack incidence and total heart attack incidence. Also, bariatric surgery was associated both with reduced number of tal stroke events and total stroke events.
CHICAGO Among obese individuals, having bariatric surgery was associated with a reduced long-term incidence of cardiovascular deaths and events such as heart attack and stroke, according to a study in the January 4 issue of JAMA.
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Lars Sjostrom, M.D., Ph.D., of the University of Gothenburg, Sweden, and colleagues conducted a study to test the hypothesis that bariatric surgery is associated with a reduced incidence of cardiovascular events and examined the relationship between weight change and cardiovascular events. The study (Swedish Obese Subjects [SOS]) is an ongoing, nonrandomized, prospective, controlled study conducted at 25 public surgical departments and 480 primary health care centers in Sweden, and includes 2,010 obese participants health risks from obesitywho underwent bariatric surgery and 2,037 matched obese controls who received usual care.
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In addition to writing CardioBrief, I cover cardiology news for CardioExchange, a social media website for cardiologists published by the New England Journal of Medicine. I was the editor of TheHeart.Org from its inception in 1999 until December 2008. Following the purchase of TheHeart.Org by WebMD in 2005 I became the editorial director of WebMD professional news, encompassing TheHeart.Org and Medscape Medical News. Prior to joining TheHeart.Org I was a freelance medical journalist and wrote for a wide variety of medical and computer publications. In 1994-1995 I was a Knight Science Journalism Fellow at MIT. I have a PHD in English from SUNY Buflo and I drove a taxicab in New York City before embarking on a cahealth risks from obesity Bariatric Surgery Cuts Cardiovascular Deaths and Eventsreer in medical journalism.You can follow me on Twitter at: @cardiobrief.
Bariatric Surgery Associated With Reduction in Cardiovascular Events and Death
Bariatric surgery results in significant reductions in cardiovascular deaths and events, according to a new study from Sweden published inJAMA. But one expert cautions that the results do not mean that obese patients without other weight-related complications should undergo surgery.
During follow-up, there were 49 cardiovascular deaths among the patients in the control group and 28 cardiovascular deaths among the patients in the surgery group. In total (tal and nontal), there were 234 cardiovascular events among patients in the control group and 199 cardiovascular events among patients in the surgery group. After adjustment for a number of variables, bariatric surgery was associated with a reduced number of tal cardiovascular deaths and a lower incidence of total cardiovascular events.
In a surprising finding, the investigators found no significant association between either weight at baseline or weight loss after surgery and cardiovascular events. The authors speculated this may have been due to the low statistical power of the study to detect an association or, alternatively, that the greatest benefit was derived from the initial modest weight loss caused by the surgery.
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health risks from obesity Bariatric Surgery Cuts Cardiovascular Deaths and Events,Analyzing data from more than 4,000 obese patients enrolled in the ongoing Swedish Obese Subjects (SOS) study, Lars Sjöström and colleagues found that bariatric surgery was associated with a reduction in cardiovascular events and deaths after a mean followup of 14.7 years. (The investigators hadpreviously reporteda reduction in total mortality in the treatment group.)
